Histomorphological variants of oral squamous cell carcinoma and their relation with prognosis of the disease

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Original Article

Author Details : Suvidhi Dhore*, Jeevika Wankhade, Sneha Dey

Volume : 8, Issue : 4, Year : 2022

Article Page : 178-183

https://doi.org/10.18231/j.jooo.2022.038

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Abstract

Background: The key to wealth is health but in present days cancer is going to exhaust mental, physical and economic conditions. Oral Cancer is the 6 most common cancer worldwide. Approximately 630,000 new patients diagnosed annually resulting in more than 350,000 deaths every year. Squamous cell carcinoma is by far the most important and the most common malignant mucosal neoplasm of the head and neck accounting for over 90% of all malignancies.
Histomorphological features of oral squamous cell carcinoma (OSCC) and their relation with the pathological prognostic factors i.e. histological stage and grade of malignancy is the key feature, which help early and easy prognosis of OSCC.
Aim: To study the histomorphological features of oral squamous cell carcinoma and their relation with the pathological prognostic factors i.e. histological stage and grade of malignancy.
Objective: Recent reports suggest an increase in oral squamous cell carcinoma (OSCC) frequency. To improve programs in public health, it is necessary to understand the epidemiological conditions.
Study Design: A retrospective review of all OSCC cases diagnosed by the Pathology Department was performed. Demographic data, in addition to anatomic zone and histological degree of differentiation were obtained. Central tendency, dispersion and prevalence rate per 100,000 individuals were determined.
Results: A total of 150 patients were diagnosed with OSCC and majority of them were men 118(79%) were men. OSCC were predominantly observed in the age of 40-60 years. The predominant anatomic zone was the Buccal mucosa, GBS, Angle of Mouth 99(66%), followed by the tongue and lip 42(28%) and Retromolar Triagone 09(06%).
The most frequent histological degree was well differentiated in 110 cases (73.3%). The rates of OSCC prevalence showed similar patterns in terms across time.

Keywords: Oral squamous cell carcinoma, Prevalence, Histology degree and anatomic zone.

How to cite : Dhore S, Wankhade J, Dey S, Histomorphological variants of oral squamous cell carcinoma and their relation with prognosis of the disease. J Oral Med Oral Surg Oral Pathol Oral Radiol 2022;8(4):178-183

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