Ductal papilloma with atypical ductal hyperplasia – Understanding the importance of immunohistochemistry- A case report

Nisarga Rani R; Anuradha C K Rao; Siddhartha Biswas; Madan K

Ductal papilloma with atypical ductal hyperplasia – Understanding the importance of immunohistochemistry- A case report

Case Report

Author Details : Nisarga Rani R*, Anuradha C K Rao, Siddhartha Biswas, Madan K

Volume : 7, Issue : 1, Year : 2022

Article Page : 60-63

https://doi.org/10.18231/j.jdpo.2022.013

Suggest article by email

Get Permission

Abstract

Solitary intraductal papilloma of the breast is a common benign mammary proliferative disease and is the most common neoplasm associated with nipple discharge in women. Women with solitary papillomas have 1.5-2.0 times increased risk of developing invasive carcinoma. The papillary lesions of the breast include a broad spectrum of disorders from benign papilloma, atypical papilloma to papillary carcinoma. Benign papilloma on core needle biopsy has been found to have concurrent malignancy in about 3–5% of cases at excision. Solid papillomas commonly pose a diagnostic dilemma due to similarities with other ominous papillary lesions. The presence of ADH within a papilloma and/or in the surrounding breast is associated with an increased risk of recurrence or invasive carcinoma. The present study undertakes to fully describe the morphological changes occurring within the epithelial component of central papillomas and to search for factors of prognostic significance concerning recurrence, progression and differentiation of atypical ductal hyperplasia.

Keywords: Ductal papilloma, ADH, Proliferative breast disease

How to cite : Nisarga Rani R, Rao A C K, Biswas S, Madan K, Ductal papilloma with atypical ductal hyperplasia – Understanding the importance of immunohistochemistry- A case report. IP J Diagn Pathol Oncol 2022;7(1):60-63

This is an Open Access (OA) journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.