The Tohoku Journal of Experimental Medicine
Online ISSN : 1349-3329
Print ISSN : 0040-8727
ISSN-L : 0040-8727
Biochemical Studies on Carbohydrates
CXCVII. Glucidamins in Yoshida Sarcoma
Kohtaroh Hasizume
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1957 Volume 65 Issue 2-3 Pages 195-204

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Abstract

1. Three glucidamins, insoluble (I) and soluble (II, III) in 90% phenol, were isolated from tumor knods on the rat omentum majus of Yoshida sarcoma in an electrophoretically pure or almost pure state.
2. The glucidamins were found to contain galactosamine, glucosamine, galactose, glucose, mannose, L-fucose and xylose and/or lyxose as sugar components in molecular proportions and amounts different from one glucidamin to another. I was comparatively rich in glucose and pentose, II in hexosamine, glucose and mannose and III in hexosamine and mannose.
3. I contained aspartic and glutamic acids, cystine, serine, glycine, lysine, threonine, arginine, alanine, proline and valine and/or methionine as amino acids, and II and III tyrosine besides those amino acids.
4. Other properties, physical and chemical, of the glucidamins were also examined.
Many thanks are due to Dr. H. Sato in the Pharmacological Institution, Tokyo, who kindly gave the sarcoma material, for the gift and to Dr. S. Tsuiki in this laboratory for his ardent help throughout this investigation. K. Hasizume.
The expenses of this work were defrayed by a grant given from the Ministry of Education through the Grant Committee for Scientific Researches. H. Masamune.

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