An internal-use medication experiment of Ninjin-to and Mao-to was performed to six healthy adult males. The radial artery pressure pulse and stroke volume before and after taking each medicines were measured for 2 hours at every of 30 minutes. Then circuit constant of the five-element electric circuit arterial model which authors reported previously was calculated from the measured radial artery pressure pulse and stroke volume. Comparison examinations were carried out among each individual on the change of the calculated circuit constant with the passage of time. As the results, the change of the radial artery pressure pulse due to the internal-use of Ninjin-to and Mao-to has been able to be shown quantitatively as change of the central and peripheral constants.