Abstract
Introduction
The association between Bisphenol A (BPA) exposure and attention deficit hyperactivity disorder (ADHD) has been a controversial topic. Objective: To evaluate the connection between BPA exposure and ADHD.
Content
We search Scopus, Web of Science, and Medline databases until August 2022. The meta-analysis was performed by using the software Stata 12.0 to calculate the combined effect value Odds ratios (OR) and 95% confidence interval (95%CI). A total of 8 studies were included in this meta-analysis, including 5,710 children. Using the random effect model, it was found that compared with the lowest level of BPA exposure, the OR (95%CI) value of urine BPA exposure and ADHD in the highest level of BPA exposure was 1.76 (1.13–2.74).
Summary and Outlook
Based on the current meta-analysis results, BPA exposure may be a significant contributing factor to the development of ADHD in children.
Acknowledgments
The author acknowledge the staff of Child Health Department of Ninghai maternal and child health hospital and Dr. Dan Xiong for supporting this systematic review for supporting this systematic review.
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Research funding: None declared.
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Author contributions: All authors have accepted responsibility for the entire content of this manuscript and approved its submission.
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Competing interests: Authors state no conflict of interest.
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Ethical approval: Not applicable.
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Supplementary Material
The online version of this article offers supplementary material (https://doi.org/10.1515/REVEH-2022-0184).
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