The psychiatric and psychosomatic aspects of muscle contraction headache (MCH) were reported in this study. 48 cases of MCH were selected. Based on a consideration of clinical course, 48 cases were divided into 4 groups : the first group consisted of MCH patients with psychosomatic trend : the second group included those with neurotic trend; the third group, those with depressive trend; the fourth group, those with transient trend.The General Health Questionnaire (GHQ) completed at first visit of our department was used for comparison of each MCH subgroup. The results of this evaluation revealed that MCH patients with neurotic trend demonstrated high total score, while those with depressive trend demostrated both high total score and depressive score, and those with psychosomatic trend demonstrated both low total score and depressive score. These results indicate the usefulness of GHQ.On the other hand, although no significant statistical difference was observed, antidepressants showed relative effect for MCH, compared with antianxietics and muscle relaxants. This effect of antidepressants was obtained either with or without the presence of depressive symptoms. This may suggest that antidepressants are also effective against pain as well as depressive symptoms. Therefore from the above results, the more frequent use of antidepressants for the treatment of MCH could be recommended.