ダウンロード数: 37
このアイテムのファイル:
ファイル | 記述 | サイズ | フォーマット | |
---|---|---|---|---|
69_2_33.pdf | 671.62 kB | Adobe PDF | 見る/開く |
タイトル: | 腎移植後に発生した悪性腫瘍の臨床的検討 |
その他のタイトル: | A Retrospective Study on the Malignancies after Renal Transplantation |
著者: | 松田, 剛 望月, 保志 迎, 祐太 中西, 裕美 光成, 健輔 松尾, 朋博 大庭, 康司郎 岩田, 隆寿 大仁田, 亨 錦戸, 雅春 松屋, 福蔵 酒井, 英樹 西野, 友哉 宮田, 康好 |
著者名の別形: | MATSUDA, Tsuyoshi MOCHIZUKI, Yasushi MUKAE, Yuta NAKANISHI, Hiromi MITSUNARI, Kensuke MATSUO, Tomohiro OHBA, Kojiro IWATA, Takahisa ONITA, Toru NISHIKIDO, Masaharu MATSUYA, Fukuzo SAKAI, Hideki NISHINO, Tomoya MIYATA, Yasuyoshi |
キーワード: | Renal transplantation Malignancy Risk factors Immunosuppressive agents |
発行日: | 28-Feb-2023 |
出版者: | 泌尿器科紀要刊行会 |
誌名: | 泌尿器科紀要 |
巻: | 69 |
号: | 2 |
開始ページ: | 33 |
終了ページ: | 39 |
抄録: | Detection of post-transplant malignant tumors and the analysis of the associated risk factors is important for monitoring the progress after renal transplantation. In this study, we retrospectively examined the medical records of 298 patients who underwent renal transplantation at two facilities in Nagasaki Prefecture (Nagasaki University Hospital and National Hospital Organization Nagasaki Medical Center). Of the 298 patients, 45 (15.1%) patients had developed malignant tumors with 50 lesions. The most common type of malignant tumor was skin cancer (eight patients; 17.8%), followed by renal cancer (six patients; 13.3%), and pancreatic cancer and colorectal cancer, (four patients; 9.0% each). Five patients (11.1%) had multiple cancers, four of whom had skin cancer. The cumulative incidence within 10 and 20 years after renal transplantation was 6.0 and 17.9%, respectively. Univariate analysis identified age at transplantation and administration of cyclosporine and rituximab as risk factors, while multivariate analysis identified age at transplantation and administration of rituximab as independent factors. The administration of rituximab was associated with the development of malignant tumors. However, further investigation is required to establish the association with post-transplant malignant neoplasms. |
著作権等: | 許諾条件により本文は2024-03-01に公開 |
DOI: | 10.14989/ActaUrolJap_69_2_33 |
URI: | http://hdl.handle.net/2433/279576 |
PubMed ID: | 36863869 |
出現コレクション: | Vol.69 No.2 |
このリポジトリに保管されているアイテムはすべて著作権により保護されています。