昭和医学会雑誌
Online ISSN : 2185-0976
Print ISSN : 0037-4342
ISSN-L : 0037-4342
Lennert's lymphomaの2例
杉山 喜彦塩川 章藤本 治道牧角 裕九島 已樹横山 新一郎鶴岡 延熹佐々木 俊輔荒 徹昭
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1984 年 44 巻 5 号 p. 707-714

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Here we reported the cases of two patients suffering from Lennert's lympncma. The first was that of a 73-year-old male. Histological examinations were twice doneand electronmicroscopic findings were obtained. The second case was that of a 73-year-old female. The first case showed histologically focal epithelioid cell clusters, partly diffuse proliferation of those cells were despersed throughout the lymph nodes. On the contrary, in the second case, proliferating lymphoid cells and epithelioid cells were limited, especially in the so-called Tzone. In both cases, proliferating lymphoid cells co-exist with epithelioid cells consisted of large immunoblast-like cells, medium-sized lymphoid cells with marked irregular nuclear margins and small lymphoid cells. Electronmicroscopically, the immunoblast-like cells and the other tumor cells had no differentiating tendencies toward plasmablasts or plasma cells. Moreover, by the PAP staining method, only a few positive cells in the lymph nodes were found in both cases. As above-mentioned, Lennert's lymphoma may suggest a malignant lymphoma of T cell origin, but, histomorphologically and clinically, it has not been clearly determined that this lymphoma has a distinct disease-causing entity.

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