INHIBITION OF CYP3A4 EXPRESSION BY KETOCONAZOLE IS MEDIATED BY DISRUPTION OF PREGNANE X RECEPTOR (PXR), STEROID RECEPTOR COACTIVATOR-1 (SRC-1), AND HEPATOCYTE NUCLEAR FACTOR 4A (HNF4A) INTERACTION

Yun Ping Lim; Sheng Chun Kuo; Ming Liang Lai; Jin ding Huang

doi:10.14896/jssxmeeting.23.0.226.0

23rd JSSX Annual meeting

Session ID : 30PE-33

DOI https://doi.org/10.14896/jssxmeeting.23.0.226.0

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Host: The Japanese Society for the Study of Xenobiotics

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INHIBITION OF CYP3A4 EXPRESSION BY KETOCONAZOLE IS MEDIATED BY DISRUPTION OF PREGNANE X RECEPTOR (PXR), STEROID RECEPTOR COACTIVATOR-1 (SRC-1), AND HEPATOCYTE NUCLEAR FACTOR 4A (HNF4A) INTERACTION

*Yun Ping Lim, Sheng Chun Kuo, Ming Liang Lai, Jin ding Huang

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