In 41 cases of ruptured intracranial aneurysms, combined ventriculo-cisternal drainage and cisternal drainage designed by us was performed after clipping of aneurysms within 48 hours after hemorrhage and the bloody cerebrospinal fluid in the basal cisterns were analyzed.
Mortality rate in this series was 9.3 per cent and symptomatic vasospasm were appeared in 7.3 percent. Out flow cerebrospinal fluid from bilateral cisterns was 300-500ml/day. Total hemoglobin in cerebrospinal fluid within one week after operation was 7.0±3.6g/dl which correspond to 46.7±23.7ml of blood. Lipoperoxide and Vit. E decreased after hemorrhage correlatively having no influence on cerebral vasospasm. Hydrogen ion concentration in the bloody cerebrospinal fluid decreased in all cases.
It may safely be concluded that the ventriculo-cisternal drainage is effective for prevention of cerebral vasospasm.