1987 Volume 29 Issue 9 Pages 1175-1179
A 43-year-old male developed anasarca, pulmonary edema and severe hypertension in the acute phase of poststreptococcal glomerulonephritis, Vigorous treatment of the anasarca with intravenous furosemide and of the hypertension with multiple antihypertensive drugs failed to control the intra-vascular volume overload and severe hypertension. The patient subsequently developed cerebral hemorrhage. The severe hypertension was controlled only by intravenous diazoxide. Reports of intracranial hemorrhage in acute poststreptococcal glomerulonephritis are very rare but the prognosis is poor. Aggressive antihypertensive therapies including diazoxide are recommended when the blood pressure is not controlled by diuretics and conventional anti-hypertensive drugs.
