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Absence of signal peptide peptidase in peripheral sensory neurons affects latency-reactivation in HSV-1 ocularly infected mice

Fig 8

Effect of SPP deficiency on virus reactivation in infected mice.

Avil-SPP-/- and control mice were ocularly infected with 2 X 105 PFU/eye of HSV-1 strain McKrae. TG from infected mice were harvested on day 28 PI and the explant reactivation assay was performed. Data points indicate the day of virus reactivation. Each point is the mean ± SEM from 34 TG.

Fig 8

doi: https://doi.org/10.1371/journal.ppat.1010281.g008