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Open Access

Correction

Correction: Site-specific analysis of N-glycans from different sheep prion strains

  • Natali Nakić,
  • Thanh Hoa Tran,
  • Mislav Novokmet,
  • Olivier Andreoletti,
  • Gordan Lauc,
  • Giuseppe Legname
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There are glycopeptide structures missing in both Fig 2 and Fig 6. Please see the correct Fig 2 and Fig 6 here.

Also, in Fig 7 the m/z value 1255.8162 is associated with the wrong glycan composition and should be assigned to H5N6S1F2. Please see the correct Fig 7 here.

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Fig 2. Detected N-184 glycopeptides on both prion strains.

Proposed glycan structures found on N-184 glycosylation site with the theoretical and observed m/z values of the detected glycopeptides. H–hexose, N–N-acetylhexosamine, F–fucose and S–N-acetylneuraminic acid (sialic acid). Blue square–N-acetylglucosamine (GlcNAc), green circle–mannose (Man), red triangle–fucose (Fuc), yellow circle–galactose (Gal), purple diamond–N-acetylneuraminic acid (Neu5Ac). The presence of MS/MS spectrum is indicated with +. N/D–not determined.

https://doi.org/10.1371/journal.ppat.1009511.g001

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Fig 6. Identified N-200 glycopeptides on both prion strains.

Proposed glycan structures found on N-200 glycosylation site with the theoretical and observed m/z values of the detected glycopeptides. H–hexose, N–N-acetylhexosamine, F–fucose and S–N-acetylneuraminic acid (sialic acid). Blue square–N-acetylglucosamine (GlcNAc), green circle–mannose (Man), red triangle–fucose (Fuc), yellow circle–galactose (Gal), purple diamond–N-acetylneuraminic acid (Neu5Ac). The presence of MS/MS spectrum is indicated with +. N/D–not determined.

https://doi.org/10.1371/journal.ppat.1009511.g002

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Fig 7. Representation of detected glycoforms on the N-200 glycosylation site of 21K slow prion strain.

A) Extracted ion chromatograms with mutual 35 glycoforms detected. B) Assigned glycoforms in MS spectrum with N-200 peptide backbone: neutral and monosialylated, C) disialylated and trisialylated glycoforms. Blue square–N-acetylglucosamine (GlcNAc), green circle–mannose (Man), red triangle–fucose (Fuc), yellow circle–galactose (Gal), purple diamond–N-acetylneuraminic acid (Neu5Ac).

https://doi.org/10.1371/journal.ppat.1009511.g003

Reference

  1. 1. Nakić N, Tran TH, Novokmet M, Andreoletti O, Lauc G, Legname G (2021) Site-specific analysis of N-glycans from different sheep prion strains. PLoS Pathog 17(2): e1009232. https://doi.org/10.1371/journal.ppat.1009232 pmid:33600485

Citation: Nakić N, Tran TH, Novokmet M, Andreoletti O, Lauc G, Legname G (2021) Correction: Site-specific analysis of N-glycans from different sheep prion strains. PLoS Pathog 17(4): e1009511. https://doi.org/10.1371/journal.ppat.1009511

Published: April 12, 2021

Copyright: © 2021 Nakić et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.