Protein kinase TgCDPK7 regulates vesicular trafficking and phospholipid synthesis in Toxoplasma gondii
Fig 7
A model for TgCDPK7 signaling.
TgCDPK7, which interacts with PIPs [8], targets trafficking of key proteins like GPI linked proteins like SAG1/3 via its ability to facilitate the phosphorylation of proteins like TgRab11a. It regulates PE metabolism in the parasite possibly via its ability to regulate enzymes involved in PL metabolism like GPAT and PAP and these events are critical for the division of T. gondii.