The role of 9-O-acetylated glycan receptor moieties in the typhoid toxin binding and intoxication
Fig 3
The role of 9-O-acetyl modification in the typhoid toxin binding.
A, Chemical structures of α2–3 and α2–6 trisaccharide motif are shown. R is H in unmodified glycans or Ac in 9-O-acetylated glycans. B-G, Shown are sensograms (B-F) and KD values (G) of PltB pentamers incubated with various concentrations of indicated glycans.