Clumping factor B is an important virulence factor during Staphylococcus aureus skin infection and a promising vaccine target
Fig 3
Loricrin in present within the skin abscess tissue of LAC::lux infected mice.
BALB/c mice were infected subcutaneously with 2x107 CFU S. aureus LAC::lux and abscess tissue was excised at 48h post-infection. Tissue was fixed, embedded in paraffin wax and sectioned before anti-loricrin staining (dark brown) was carried out. Low power field of the entire abscess structure is shown (A). Relevant tissue sections are shown in high power fields: skin epidermal layer (B) and abscess wall (C). Black arrows indicate the presence of loricrin. Representative images of n = 3 stained sections.