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A role for domain I of the hepatitis C virus NS5A protein in virus assembly

Fig 6

Quantification of the effect of the V67A and P145A mutations on the size of LD.

A LDs in Huh7.5 cells electroporated with the indicated JFH-1 constructs were visualized by staining with BODIPY 558/568-C12. B The size of individual LD was determined and plotted as a histogram. The area (μm2) is taken as an indication of the three-dimensional volume of the LD. For comparison similar data was determined from uninfected Huh7.5 cells.

Fig 6

doi: https://doi.org/10.1371/journal.ppat.1006834.g006