BET-Inhibitors Disrupt Rad21-Dependent Conformational Control of KSHV Latency
Fig 3
Time course of KSHV transcript response to various BET inhibitors.
RT-qPCR for c-myc, LANA, ORF50 and PAN relative to actin in BCBLI cells treated with 1%DMSO, or 4uM JQ1 (A), 4uM IBET-151 (B) or 4uM BIC1 (C) for the indicated times. DMSO was used as control. The data are expressed as fold change of the treated versus untreated (DMSO) cells. * P < 0.05 ** P < 0.01 *** P < 0.001.