The Two-Component System ArlRS and Alterations in Metabolism Enable Staphylococcus aureus to Resist Calprotectin-Induced Manganese Starvation
Fig 5
ArlRS enhances gene expression in response to calprotectin.
WT S. aureus (Newman) and ΔarlRS were grown in rich medium in the presence and absence of 240 μg/ml of CP and transcript levels of the threonine/serine deaminase (NWMN_1348) was assessed by qRT-PCR. Expression was compared to wild type bacteria grown in the absence of CP. * = p≤0.05 by one-way ANOVA with Sidak’s multiple comparisons test. Error bars indicate SD. n≥3.