The Epstein-Barr Virus BART miRNA Cluster of the M81 Strain Modulates Multiple Functions in Primary B Cells
Fig 5
The miRNA subcluster1 is mainly but not exclusively responsible for the control of BZLF1 expression.
The figure shows Western blot analyses of LCLs generated with M81, M81/ΔAll, M81/ΔC1, M81/ΔC2, M81/ΔC1C2, M81/Δb2, M81/ΔZR with a BZLF1-specific antibody. The LCLs were stained at 42 (A) and 101 (B) days post-infection. The relative intensity of the signals were quantified using the ImageJ software and are also displayed as a graph of bars. One more sample is shown in S5 Fig. (C) and (D) We determined BALF5 expression level in multiple LCLs transformed with M81 and M81/ΔAll (C) and M81/Δb2 by western blot (D), and depict the results as a graph of bars after Image J quantification. All LCLs shown in (C) and (D) were investigated between 40–43 days post infection.