Sheep and Goat BSE Propagate More Efficiently than Cattle BSE in Human PrP Transgenic Mice
Figure 8
Brain PrPC expression in homozygous tg340 mouse line in comparison to both tg650 mice and human brain.
A) Immunoblots of the brain PrPC expression in tg340 detected with Pri 308 Mab. Direct sample (10% brain homogenates) and ΒΌ dilutions were loaded on 12% Bis-Tris gels. The figure illustrates a representative set of three independent experiments. B) Brain PrPC expression in tg340 in comparison to tg650 detected with Pri 308 Mab. Inmunoblots illustrates a representative set of three independent experiments and the diagrams represent the mean densytometric values data from these experiments. Data from human brains (Human) were considered as 1 relative unit. Error bars represent the standard deviation of the mean values.