Quorum Sensing Coordinates Brute Force and Stealth Modes of Infection in the Plant Pathogen Pectobacterium atrosepticum
Figure 5
Schematic Model of the Hierarchical Relationships Between ExpI, Other Regulators and Virulence Factors in Pectobacterium.
OHHL is believed to act via antagonism of the LuxR-family AHL-responsive transcriptional regulator, VirR, in turn activating or repressing numerous other regulators that control virulence factor gene expression. A second LuxR-type repressor, ExpR, may also contribute to OHHL regulation of downstream genes. This model represents an integrated summary of regulatory data derived from the study of multiple Pectobacterium strains, and is unlikely to apply in every aspect to all such strains. Adapted from von Bodman et al., [41] using additional information from Barnard and Salmond [16], and this study. Solid arrowheads indicate activation and bars indicate repression. Dotted lines indicate uncertain and/or strain dependent effects.