Differential Regulation of Caspase-1 Activation, Pyroptosis, and Autophagy via Ipaf and ASC in Shigella-Infected Macrophages
Figure 6
Endogenous LC3-I to LC3-II Conversion in BMMs Infected by Shigella
Wild-type, caspase-1-deficient, Ipaf-deficient, or ASC-deficient BMMs were infected with Shigella WT, ΔvirG, or TTSS mutant S325. At 30 min after infection, the total lysates of BMMs were prepared and analyzed by western blotting using anti-LC3 antibody. The immunoblot for β-actin was indicated as an internal control.