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Effects of MDMA-assisted therapy for PTSD on self-experience

Fig 4

Significant differences in CAPS-5 total severity change scores between treatment groups by baseline self-experience levels.

Interaction between treatment and baseline alexithymia subgroup levels was statistically significant to warrant further stratification (p = 0.04); and stratified results also presented for self-compassion and IASC scores. At baseline, being (i) worse-off, having borderline alexithymia/ alexithymia or low self-compassion or (ii) better-off, lower idealization disillusionment, identity impairment, identity diffusion, or susceptibility to influence were associated with statistically significant greater CAPS-5 changes scores in the MDMA-assisted therapy group compared to Therapy with placebo, at alpha p ≤ .05 (*). For all other IASC factors, there were no differences in CAPS-5 change scores by baseline subgroup levels.

Fig 4

doi: https://doi.org/10.1371/journal.pone.0295926.g004