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Retraction

Retraction: The Gastroprotective Effect of Vitex pubescens Leaf Extract against Ethanol-Provoked Gastric Mucosal Damage in Sprague-Dawley Rats

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Following the publication and correction of this article [1, 2], concerns were raised regarding reuse of results presented in presented in Figs 9 and 10. Specifically,

  • Fig 9, the following panels appear to partially overlap, despite being used to represent different experimental conditions:
    1. ○ Panel G4 and panel G5
    2. ○ Panel G7 of this article [1] and Fig 6d of [3, retracted in 4]* when rotated
  • Fig 10, the following panels appear to fully or partially overlap, despite being used to represent different experimental conditions:
    1. ○ Panel G1 of this article [1] and Fig 5A of [5]*
    2. ○ Panel G3 of this article [1] and Fig 10E of [6]
    3. ○ Panel G5 of this article [1] and Fig 10D of [6]
    4. ○ Panel G7 of this article [1] and Fig 10C of [6]

Some of the similar (or reused) images were used to represent controls in these articles, but different methodological details were reported for the indicated experiments in the articles’ Materials and Methods sections. Given the nature and extent of the issues, the PLOS ONE Editors are concerned about the reliability of data management and/or reporting for this study [1].

A co-author on the article responded that they were unable to retrieve the original data underlying this study, and requested the retraction of the article.

In light of the above concerns, the PLOS ONE Editors retract this article.

Some figure panels discussed above appear to report previously published material that are offered under a CC BY license, but the original articles were not attributed in [1]. For these images, the * by the citation, above, marks the oldest publication of the image of which PLOS is aware.

The Fig 10 panel G1 results report material from [5], published in 2015 by Ibrahim et al, under a CC-BY-NC 3.0 license. Due to restrictions that apply to the original article’s license, this figure is excluded from the PLOS article’s [1] CC BY 4.0 license. At the time of retraction, the article [1] was republished to note this exclusion in the Fig 10 legend and the article’s copyright statement.

SMN and MAA agreed with the retraction. MH responded but expressed neither agreement nor disagreement with the editorial decision. NSAW, MFH, SMD, DAB, SMS, ER, HK, RA, AHSA, and HMA either did not respond directly or could not be reached. SMN apologizes for the issues with the published article. MAA stands by the article’s findings.

References

  1. 1. Saeed AL-Wajeeh N, Halabi MF, Hajrezaie M, M. Dhiyaaldeen S, Abdulaziz Bardi D, M. Salama S, et al. (2016) The Gastroprotective Effect of Vitex pubescens Leaf Extract against Ethanol-Provoked Gastric Mucosal Damage in Sprague-Dawley Rats. PLoS ONE 11(9): e0157431. https://doi.org/10.1371/journal.pone.0157431
  2. 2. AL-Wajeeh NS, Halabi MF, Hajrezaie M, Dhiyaaldeen SM, Abdulaziz Bardi D, Salama SM, et al. (2017) Correction: The Gastroprotective Effect of Vitex pubescens Leaf Extract against Ethanol-Provoked Gastric Mucosal Damage in Sprague-Dawley Rats. PLoS ONE 12(5): e0179072. https://doi.org/10.1371/journal.pone.0179072
  3. 3. Halabi MF, Shakir RM, Bardi DA, Al-Wajeeh NS, Ablat A, Hassandarvish P, et al. (2014) Gastroprotective Activity of Ethyl-4-[(3,5-di-tert-butyl-2-hydroxybenzylidene) Amino]benzoate against Ethanol-Induced Gastric Mucosal Ulcer in Rats. PLoS ONE 9(5): e95908. https://doi.org/10.1371/journal.pone.0095908 pmid:24800807
  4. 4. The PLOS ONE Editors (2023) Retraction: Gastroprotective Activity of Ethyl-4-[(3,5-di-tert-butyl-2-hydroxybenzylidene) Amino]benzoate against Ethanol-Induced Gastric Mucosal Ulcer in Rats. PLoS ONE 18(11): e0294007. https://doi.org/10.1371/journal.pone.0294007
  5. 5. Ibrahim IAA, Abdulla M, Hajrezaei M, Bader A, Shahzad N, Al-Ghamdi SS, et al. (2016) The gastroprotective effects of hydroalcoholic extract of Monolluma quadrangula against ethanol-induced gastric mucosal injuries in Sprague Dawley rats. Drug Design, Development and Therapy 10: 93–105. https://doi.org/10.2147/DDDT.S91247
  6. 6. Saremi K, Rad SK, Tayeby F, Abdulla MA, Karimian H, Majid NA (2019) Gastroprotective activity of a novel Schiff base derived dibromo substituted compound against ethanol-induced acute gastric lesions in rats. BMC Pharmacology and Toxicology, 20: 13. https://doi.org/10.1186/s40360-019-0292-z pmid:30770761

Citation: The PLOS ONE Editors (2023) Retraction: The Gastroprotective Effect of Vitex pubescens Leaf Extract against Ethanol-Provoked Gastric Mucosal Damage in Sprague-Dawley Rats. PLoS ONE 18(11): e0294006. https://doi.org/10.1371/journal.pone.0294006

Published: November 10, 2023

Copyright: © 2023 The PLOS ONE Editors. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.