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An atopic dermatitis-like murine model by skin-brushed cockroach Per a 2 and oral tolerance induction by Lactococcus lactis-derived Per a 2

Fig 3

Changes in serum total IgE (A) and Per a 2-specific IgE (B), -IgG1(C), and -IgG2a (D) antibodies in murine groups as indicated in weeks. * denotes p<0.05, ** denotes p<0.01, *** denotes p<0.001, ns denotes not statistically significant by one-way analysis of variance with the Bonferroni multiple range test.

Fig 3

doi: https://doi.org/10.1371/journal.pone.0291162.g003