Mice lacking nucleotide sugar transporter SLC35A3 exhibit lethal chondrodysplasia with vertebral anomalies and impaired glycosaminoglycan biosynthesis
Fig 3
Slc35a3 mRNA was expressed in the presomitic mesoderm during somite formation.
Whole-mount in situ hybridization images of wild-type mouse embryos at E9.25 (somite 20–22) produced using the antisense (A, B) and the sense (C) probes against Slc35a3 mRNA. Lateral side view (A), and the magnified images of the tail region (B, C). NE: neuroepithelium, PSM: presomatic mesoderm. Scale bars: 500 μm. The same results were obtained from two independent experiments.