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LC-MS/MS-based serum proteomics reveals a distinctive signature in a rheumatoid arthritis mouse model after treatment with mesenchymal stem cells

Fig 4

L-1000 analysis of cell culture supernatants of hUCB-MSCs for identification of secreted protein about regulating RA.

(A) Heatmap analysis of genes in three samples after treatment with hUCB-MSCs analyzed by L-1000 using MEV program. Colors of columns represent relative abundances. Columns indicate the abundance with different colors as indicated in the legend (blue, lower abundance; red, higher abundance). (B) GO terms in the enrichment analysis of genes affected by hUCB-MSCs. Higher significance is indicated by red and lower significance is indicated by yellow as described in the legend. The position of the circle changes according to fold enrichment.

Fig 4

doi: https://doi.org/10.1371/journal.pone.0277218.g004