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Thermoregulatory heat-escape/cold-seeking behavior in mice and the influence of TRPV1 channels

Fig 5

Representative photoimages of cFos-immunoreactive (cFos-IR) cells.

Representative photoimages of cFos-IR cells in two sections (bregma 0.4 and 0.14 mm) in the preoptic area of the hypothalamus (POA) of the control (CON) group at Ta of 28°C (Aa, Ae, and Ai), capsaicin (CAP) group at Ta of 28°C (Ab, Af, and Aj), CON group at Ta of 37°C (Ac, Ag, and Ak), and CAP group at Ta of 37°C (Ad, Ah, and Al). The areas indicated in the dashed circles are the ventromedial POA (VMPO) (Fig 5Aa–5Ad), median POA (MnPO) (Fig 5Ae–5Ah), and medial POA (MPO) (Fig 5Ai–5Al). The areas are indicated as grey areas in the illustrations (Fig 5B; “a,” “b,” and “c” correspond to the VMPO, MnPO, and MPO, respectively), which were adapted from the Allen Mouse Brain Atlas [45]. Scale bar, 200 μm; 3V, third ventricle; ac, anterior commissure.

Fig 5

doi: https://doi.org/10.1371/journal.pone.0276748.g005