Interleukin-17, a salivary biomarker for COVID-19 severity
Fig 2
Increased IL-17 level in saliva of severe COVID-19 patients associated with higher need for mechanical ventilation and/or death by days 29.
Kaplan–Meier survival curves of the need for mechanical ventilation (A-C) and/or death (D-F), based on the IL-17, TNFα, and IL-1β cytokine levels in saliva of patients with severe COVID-19 (n = 53). Statistical test: Cox proportional models adjusted for patient’s demographics factors (age, gender, and body mass index), comorbidities (diabetes mellitus), and COVID-19 related severity serum markers (D-dimer, CRP, and ferritin), with significance indicated by P value of less than 0.05.