Development of transgenic models susceptible and resistant to SARS-CoV-2 infection in FVB background mice
Fig 5
Histopathological analysis of lungs of SARS-CoV-2 infected K18-hACE2 and CAG-hACE2 transgenic mice.
Lung section of a K18-hACE2 mouse of the NC group (A), VL group (C, D), VH group (G, H) and a CAG-hACE2 mouse of the NC group (B), VL group (E, F), VH group (I, J) on 2 dpi or 6 to 7 dpi. Interstitial pneumonia (black star); bronchiolitis (white star); perivascular edema (arrowhead); (magnification x100).