5-ethyl-2’-deoxyuridine fragilizes Klebsiella pneumoniae outer wall and facilitates intracellular killing by phagocytic cells
Fig 4
K2 is active at a concentration of 3 μM and above.
A. The effect of K2 on the intracellular killing of K. pneumoniae was determined as described in the legend to Fig 3 at concentrations of K2 ranging from 1 to 30 μM. K2 increased intracellular killing of bacteria at 3 μM (blue), 10 μM (purple) and 30 μM (green) (mean ± SEM; *: p<0.05; Kruskal-Wallis test, Dunn’s test. DMSO, 3 μM and 10 μM: N = 6; 1 μM: N = 5; 30 μM: N = 4 independent experiments). B. The corresponding survival curves of ingested K. pneumoniae are shown.