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Association between history of HBV vaccine response and anti-SARS-CoV-2 spike antibody response to the BioNTech/Pfizer’s BNT162b2 mRNA SARS-CoV-2 vaccine among healthcare workers in Japan: A prospective observational study

Fig 1

Spike protein antibody levels of patients in the study.

(A) Distribution of SARS-CoV-2 spike protein antibody titers (logarithmic scale) at baseline, after one dose of BNT162b2 mRNA-1273 COVID-19 vaccine, and after two doses (n = 954). (B) Distribution of SARS-CoV-2 spike protein antibody titers (logarithmic scale) after a single dose of BNT162b2 mRNA-1273 COVID-19 vaccine, stratified by age groups (n = 954). (C) Distribution of SARS-CoV-2 spike protein antibody titers (logarithmic scale) after a single dose of BNT162b2 mRNA-1273 COVID-19 vaccine, stratified by history of HBV vaccine response (n = 954).

Fig 1

doi: https://doi.org/10.1371/journal.pone.0268529.g001