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Protein interactions with metallothionein-3 promote vectorial active transport in human proximal tubular cells

Fig 2

Intracellular localization of MT-3 in a doming population of HK-2(MT-3) cells.

MT-3 (green) is seen in a non-doming monolayer (A-E), a moderately tall dome (F-J), and in a taller dome structure (K-O). Nuclei are stained with DAPI (blue). The z-section level (0.35 μm depth) relative to the total number of z-sections through that region is indicated as a ratio in the upper right corner of each image. The scale bar at the bottom right of each image shows increments of 5 μm up to 25 μm.

Fig 2

doi: https://doi.org/10.1371/journal.pone.0267599.g002