Effects of Korean red ginseng on three-dimensional trabecular bone microarchitecture and strength in growing rats: Comparison with changes due to jump exercise
Fig 1
Micro-CT analyses of trabecular bone microarchitecture in the distal femoral metaphysis.
A) Representative 3D images of the femoral trabecular bone architecture scanned by micro-CT. B) The distal femoral metaphysis was scanned in an area 2.8–3.0 mm proximal to the distal end of the femur, including the border between the metaphysis and growth plate (GP). C) The region of interest selected for analysis, including cortical and trabecular bone of the distal femoral metaphysis (130 slices). D) Cortical and trabecular bone were subsequently separated and 3D structural indices were calculated. E) After analyzing the trabecular bone architecture, samples were subjected to FEA for prediction of fracture loads. The nodes located at the proximal surface of the femur was fully fixed in all directions, and compression test was simulated at a load of 400N applied to the distal surface of the femur.