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Human immune globulin treatment controls Zika viremia in pregnant rhesus macaques

Fig 1

Animal demographics and study timeline.

(A) Animal ID, animal age at the time of ZIKV or mock inoculation, gestational day (GD) at the time of infection, and gestational day at the time of cesarean section (C-section). Each study arm is represented in subsequent graphs by the color shown in the monkey for each group. (B) Timeline representing the day of inoculation, treatment, blood sampling (ticks on the line), and C-section for animals in this study relative to either days post-inoculation (dpi) or gestational day (GD). Blood sampling occurred as shown through 27 dpi and then was twice weekly until two consecutive time points were negative for ZIKV RNA and then sampling was once weekly.

Fig 1

doi: https://doi.org/10.1371/journal.pone.0266664.g001