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Relating the cortical visual contrast gain response to spectroscopy-measured excitatory and inhibitory metabolites in people who experience migraine

Fig 1

Stimulus example and exemplary spectra from a typical control participant.

(A) An example MRS spectrum with approximate peak assignments for known brain metabolites from a 25 year old female participant before stimulation. The FWHM of the peaks were 12 Hz and the SNR was 56, typical of the MRS quality before and after stimulation. The location of the MRS voxel is shown overlaid on the 3D T1 weighted images (inset). (B) Diagram of the flashing checkerboard frames shown during visual cortex stimulation.

Fig 1

doi: https://doi.org/10.1371/journal.pone.0266130.g001