Effects of different doses of complete Freund’s adjuvant on nociceptive behaviour and inflammatory parameters in polyarthritic rat model mimicking rheumatoid arthritis
Fig 8
Histological sections of the CFA-inoculated hind paw tissues in (A) control, (B) CFA 5.0, (C) CFA 7.5 and (D) CFA 10.0 subjected to haematoxylin and eosin (H&E) staining at 400x magnification.
The control group demonstrated no significant lesion appearance in the mineral oil-injected hind paw. Meanwhile, extensive inflammatory cells infiltration was observed in CFA 10.0 group, (D) mild and moderate level of inflammatory cells infiltration were detected in CFA 5.0 (B) and CFA 7.5 (C), respectively. The arrow indicates the extensive inflammatory cells infiltration at the injected hind paw tissue.