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Effects of functional variants of vitamin C transporter genes on apolipoprotein E E4-associated risk of cognitive decline: The Nakajima study

Fig 2

Genotype-specific differences in transcript levels of vitamin C transporter gene.

These data were cited from the GTEx Portal on 11/01/2020 (https://gtexportal.org/). In the “GTEx” Portal database, a significant correlation was observed between the genotype of each SNV and the transcript level of SLC23A2 or SLC2A1 in human tissues. The p value indicates a significant difference between gene expressions by genotype. The genotype-expression association data for tissues with the lowest p values are presented for the 49 human tissues in the “GTEx” Portal database. (A) The transcription level of SLC2A1 in the left ventricle by rs710218 genotype. (B) The transcription level of SLC2A1 in the left ventricle by rs841851 genotype. (C) The transcription level of SLC23A2 in the spleen by rs1279683 genotype.

Fig 2

doi: https://doi.org/10.1371/journal.pone.0259663.g002