Multimodal imaging and functional analysis of the chick NMDA retinal damage model
Fig 4
SD-OCT analysis of NMDA-treated and corresponding control eyes.
Representative b-scans of D1 vehicle (saline, left) and D1 NMDA (right) showing edema in IPL (A), D7 vehicle (saline, left) and D7 NMDA (right) (B), and D14 vehicle (saline, left) and D14 NMDA (right) (C). (D) Analysis of retinal thicknesses of the IPL, RNFL-IPL combined, INL, and total thickness between NMDA and saline (vehicle) treated eyes at P7/D1 to P21/D14 post injection and their respective age-matched untreated controls. Black brackets show IPL thickness, white brackets show INL thickness, asterisk denotes hyperreflective layer. Error bars are shown as standard deviation. Abbreviations: RNFL—retinal nerve fiber layer, IPL—inner plexiform layer, INL—inner nuclear layer, ONL—outer nuclear layer, RPE—retinal pigment epithelium.