Original antigenic sin responses to Betacoronavirus spike proteins are observed in a mouse model, but are not apparent in children following SARS-CoV-2 infection
Fig 3
HKU1 antibodies are prevalent in healthy children and children with acute COVID-19 and MIS-C.
SARS-CoV-2 (A) and HKU1 (B) spike IgG antibody titers and FRNT neutralization titers (C) in healthy pediatric controls compared to children hospitalized with acute COVID-19 and MIS-C. Each dot represents a unique patient, and data represent the geometric mean titers of *P<0.05; **P<0.01; ***P<0.005; ****P<0.001.