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Nationwide surveillance of AIDS-defining illnesses among HIV patients in Japan from 1995 to 2017

Fig 1

Incidence trends of acquired immunodeficiency syndrome (AIDS)-defining illnesses (ADIs).

(A) Change in the number of reported cases of ADIs over time (based on the questionnaire sent to human immunodeficiency virus [HIV]/AIDS referral hospitals across Japan). The total number of patients and episodes encountered in 2017 was 320 and 391, respectively. The numbers indicate a continuously decreasing trend since 2012. (B) Cumulative incidence and proportion of ADIs between 1995 and 2017. Pneumocystis pneumonia (PCP) occurred the most frequently, followed by cytomegalovirus (CMV) infection, candidiasis, tuberculosis (TB), Kaposi sarcoma, and non-tuberculous mycobacterial (NTM) infection.

Fig 1

doi: https://doi.org/10.1371/journal.pone.0256452.g001