Impact of different frequencies of controlled breath and pressure-support levels during biphasic positive airway pressure ventilation on the lung and diaphragm in experimental mild acute respiratory distress syndrome
Fig 7
Real-time polymerase chain reaction analysis of biological markers for proteolysis [muscle RING finger-1 (MuRF-1) and muscle atrophy F-box (MAFbx/atrogin-1)].
Box plots represent the median and interquartile range of 8 animals. Relative gene expression was calculated as a ratio of the average gene expression levels compared with the reference gene (36B4) and expressed as fold change relative to respective NV (nonventilated). Comparisons between BIVENT-100+PSV0% and BIVENT-50+PSV0% groups were done by the Mann–Whitney U test (p<0.05). For comparisons within BIVENT-50 groups, the Kruskal-Wallis test with Dunn’s post-hoc test was used (p<0.05).