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Cleroda-4(18),13-dien-15,16-olide as novel xanthine oxidase inhibitors: An integrated in silico and in vitro study

Fig 4

IC50 values of xanthine oxidase inhibitory activity of clerodane diterpenes (3 and 4).

Values were presented as mean ± standard deviation (n = 3). Statistical analyses were performed using one-way ANOVA with Tukey’s multiple comparison test and *** means p < 0.0001.

Fig 4

doi: https://doi.org/10.1371/journal.pone.0253572.g004