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Autophagy activity in cholangiocarcinoma is associated with anatomical localization of the tumor

Fig 10

Cytotoxicity of 5-FU and Sorafenib in cholangiocarcinoma (CC) and hepatocellular carcinoma (HCC) cell lines.

The intrahepatic CC (HuH-28), extrahepatic CC (TFK-1) and HCC (HepG2) cells were treated with 10–400 μM of 5-FU and 5–25 μM of Sorafenib for 48 and 72 h. Cell viability was determined by the Sulforhodamine B colorimetric assay and expressed as mean (n = 4) ± S.D.

Fig 10

doi: https://doi.org/10.1371/journal.pone.0253065.g010