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Associations of ultrasound-based inflammation patterns with peripheral innate lymphoid cell populations, serum cytokines/chemokines, and treatment response to methotrexate in rheumatoid arthritis and spondyloarthritis

Fig 4

Clustering of patients based on serum cytokines/chemokines.

A heatmap representing the serum levels of 20 biomarkers and dendrograms illustrating hierarchical clustering of these cytokines/chemokines and patients (n = 99). The clinical diagnosis (rheumatoid arthritis vs. spondyloarthritis) and the ultrasound-based inflammation pattern (Group 1 vs. Group 2) are provided below the heatmap.

Fig 4

doi: https://doi.org/10.1371/journal.pone.0252116.g004