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Coordinated changes in the expression of Wnt pathway genes following human and rat peripheral nerve injury

Fig 5

Wnt5a/b is expressed by Schwann cells in the injured rat nerve.

A-E, Triple label Immunohistochemistry for Wnt5a/b, S100 and NF on transversal sections of rat peripheral nerve 28d after sciatic nerve crush. Wnt5a/b (B, green) is predominantly expressed in S100 positive Schwann cells (C, red) that enwrap neurofilament positive axons (D, white) in the injured rat nerve (E, overlay of panels A, B, C and D). Scale bar is 10μm.

Fig 5

doi: https://doi.org/10.1371/journal.pone.0249748.g005