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Physiologically based metformin pharmacokinetics model of mice and scale-up to humans for the estimation of concentrations in various tissues

Table 6

Metformin pharmacokinetic parameters for different tissues following a single 500mg, 1000mg, and 1500mg PO dose in humans.

Table 6

doi: https://doi.org/10.1371/journal.pone.0249594.t006