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Naturally-derived protein extract from Gryllus bimaculatus improves antioxidant properties and promotes osteogenic differentiation of hBMSCs

Fig 7

ALP activity in the presence of CPI.

(a) Representative immunohistochemical (IHC) staining for alkaline phosphatase (ALP) on hBMSCs in control and CPI-treated medium at indicated time intervals. Positive staining is indicated by red-brown cytoplasm followed by hematoxylin counter staining of nucleus. Asterisks with ‘*’ indicates mild reaction, ‘**’ indicates moderate reaction, and ‘***’ indicates intense reaction, (b) their corresponding IHC scores. Statistical significance at *p < 0.05.

Fig 7

doi: https://doi.org/10.1371/journal.pone.0249291.g007