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Synergistic effect and ultrastructural changes in Trypanosoma cruzi caused by isoobtusilactone A in short exposure of time

Fig 6

Evaluation of the interference of isoobtusilactone A on infection of host cells.

Nucleus (N); kinetoplast (K); intense cytoplasm disorganization (Black arrow). A: Percentage of infected cells by trypomastigotes (p<0.05 by Tukey); B: Number of amastigotes per infected cells (p<0.05 by Tukey); C: Transmission electron micrographs showing the morphology of infected cells with untreated trypomastigotes; D: Scanning electron micrographs showing the morphology of host cells after infection with treated trypomastigotes; E-F: Transmission electron micrographs showing the morphology of infected cells with treated trypomastigotes.

Fig 6

doi: https://doi.org/10.1371/journal.pone.0245882.g006